GLUL anticorps

N° du produit ABIN7464227

Cet anticorps anti-GLUL est un anticorps Lapin Polyclonal détectant GLUL dans WB, IHC, IF, IHC (p), ICC, IP, IHC (fro) et IHC (wm). Adapté pour Humain.

Aperçu rapide pour GLUL anticorps (ABIN7464227)

Antigène: GLUL (Glutamate-Ammonia Ligase (GLUL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLUL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Whole Mount) (IHC (wm))

Classe de qualité: KO Validated

Détail du produit anti-GLUL anticorps

Réactivité croisée: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Purification: Purified by antigen-affinity chromatography.

Immunogène: Full length human Glutamine synthetase Recombinant protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , DDDDK-tagged GLUL-transfected 293T

Validation: KO/KD, Orthogonal, Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur GLUL

Antigène: GLUL (Glutamate-Ammonia Ligase (GLUL))

Autre désignation: glutamate-ammonia ligase

Sujet: Glutamate-ammonia ligase , GLNS , GS , PIG43 , PIG59,Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling (Haberle et al., 2005 [PubMed 16267323]). Fetal glutamine requirements are very high and depend largely on active glutamine synthesis and the release of glutamine into the fetal circulation by the placenta. Glutamine synthetase (EC 6.3.1.2), also called glutamate-ammonia ligase (GLUL), is expressed throughout the body and plays an important role in controlling body pH and in removing ammonia from the circulation. The enzyme clears L-glutamate, the major neurotransmitter in the central nervous system, from neuronal synapses (see references in Clancy et al., 1996 [PubMed 8975719]).[supplied by OMIM]

Poids moléculaire: 42 kDa

ID gène: 2752

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion